| St. Louis City SC vs. Orlando City SC | 6-25-2025
Wednesday
7:30 PM | Energizer Park in St. Louis, MO | View Tickets |
| Houston Dynamo FC vs. St. Louis City SC | 6-28-2025
Saturday
7:30 PM | Shell Energy Stadium in Houston, TX | View Tickets |
| Real Salt Lake vs. St. Louis City SC | 7-5-2025
Saturday
7:30 PM | America First Field in Sandy, UT | View Tickets |
| St. Louis City SC vs. Portland Timbers | 7-13-2025
Sunday
6:00 PM | Energizer Park in St. Louis, MO | View Tickets |
| FC Dallas vs. St. Louis City SC | 7-19-2025
Saturday
7:30 PM | Toyota Stadium in Frisco, TX | View Tickets |
| St. Louis City SC vs. Minnesota United FC | 7-26-2025
Saturday
7:30 PM | Energizer Park in St. Louis, MO | View Tickets |
| St. Louis City SC vs. Nashville SC | 8-9-2025
Saturday
7:30 PM | Energizer Park in St. Louis, MO | View Tickets |
| Chicago Fire FC vs. St. Louis City SC | 8-16-2025
Saturday
7:30 PM | SeatGeek Stadium in Bridgeview, IL | View Tickets |
| North Texas SC vs. St. Louis City SC 2 | 8-16-2025
Saturday
7:45 PM | Choctaw Stadium in Arlington, TX | View Tickets |
| Vancouver Whitecaps FC vs. St. Louis City SC | 8-23-2025
Saturday
6:30 PM | BC Place Stadium in Vancouver, Canada | View Tickets |
| St. Louis City SC vs. Houston Dynamo FC | 8-30-2025
Saturday
7:30 PM | Energizer Park in St. Louis, MO | View Tickets |
| St. Louis City SC vs. FC Dallas | 9-6-2025
Saturday
7:30 PM | Energizer Park in St. Louis, MO | View Tickets |
| CF Montreal vs. St. Louis City SC | 9-13-2025
Saturday
7:30 PM | Stade Saputo in Montreal, Canada | View Tickets |
| San Jose Earthquakes vs. St. Louis City SC | 9-20-2025
Saturday
7:30 PM | PayPal Park in San Jose, CA | View Tickets |
| St. Louis City SC vs. Los Angeles FC | 9-27-2025
Saturday
7:30 PM | Energizer Park in St. Louis, MO | View Tickets |
| Austin FC vs. St. Louis City SC | 10-4-2025
Saturday
7:30 PM | Q2 Stadium in Austin, TX | View Tickets |
| St. Louis City SC vs. Real Salt Lake | 10-18-2025
Saturday
8:00 PM | Energizer Park in St. Louis, MO | View Tickets |
