| Bayer 04 Leverkusen vs. FC Heidenheim | 11-8-2025
Saturday
TBD | Bay Arena in Leverkusen, Germany | View Tickets |
| VfL Wolfsburg vs. Bayer 04 Leverkusen | 11-22-2025
Saturday
TBD | Volkswagen Arena in Wolfsburg, Germany | View Tickets |
| UEFA Champions League: Manchester City FC vs. Bayer 04 Leverkusen | 11-25-2025
Tuesday
TBD | Etihad Stadium in Manchester, United Kingdom | View Tickets |
| Bayer 04 Leverkusen vs. Borussia Dortmund | 11-29-2025
Saturday
TBD | Bay Arena in Leverkusen, Germany | View Tickets |
| FC Augsburg vs. Bayer 04 Leverkusen | 12-6-2025
Saturday
TBD | WWK Arena in Augsburg, Germany | View Tickets |
| UEFA Champions League: Bayer 04 Leverkusen vs. Newcastle United FC | 12-10-2025
Wednesday
TBD | Bay Arena in Leverkusen, Germany | View Tickets |
| RB Leipzig vs. Bayer 04 Leverkusen | 12-20-2025
Saturday
TBD | Red Bull Arena in Leipzig, Germany | View Tickets |
| Bayer 04 Leverkusen vs. VfB Stuttgart | 1-10-2026
Saturday
TBD | Bay Arena in Leverkusen, Germany | View Tickets |
| Hamburger SV vs. Bayer 04 Leverkusen | 1-14-2026
Wednesday
TBD | Volksparkstadion in Hamburg, Germany | View Tickets |
| TSG 1899 Hoffenheim vs. Bayer 04 Leverkusen | 1-17-2026
Saturday
TBD | PreZero Arena in Sinsheim-Hoffenheim, Germany | View Tickets |
| Bayer 04 Leverkusen vs. SV Werder Bremen | 1-24-2026
Saturday
TBD | Bay Arena in Leverkusen, Germany | View Tickets |
| UEFA Champions League: Bayer 04 Leverkusen vs. Villarreal CF | 1-28-2026
Wednesday
TBD | Bay Arena in Leverkusen, Germany | View Tickets |
| Borussia Monchengladbach vs. Bayer 04 Leverkusen | 2-7-2026
Saturday
TBD | Borussia Park in Mönchengladbach, Germany | View Tickets |
| Bayer 04 Leverkusen vs. FC St. Pauli | 2-14-2026
Saturday
TBD | Bay Arena in Leverkusen, Germany | View Tickets |
| Bayer 04 Leverkusen vs. FSV Mainz 05 | 2-28-2026
Saturday
TBD | Bay Arena in Leverkusen, Germany | View Tickets |
| SC Freiburg vs. Bayer 04 Leverkusen | 3-7-2026
Saturday
TBD | Europa-Park Stadion in Freiburg im Breisgau, Germany | View Tickets |
| Bayer 04 Leverkusen vs. FC Bayern Munich | 3-14-2026
Saturday
TBD | Bay Arena in Leverkusen, Germany | View Tickets |
| Bayer 04 Leverkusen vs. VfL Wolfsburg | 4-4-2026
Saturday
TBD | Bay Arena in Leverkusen, Germany | View Tickets |
| Borussia Dortmund vs. Bayer 04 Leverkusen | 4-11-2026
Saturday
TBD | Westfalenstadion in Dortmund, Germany | View Tickets |
| Bayer 04 Leverkusen vs. FC Augsburg | 4-18-2026
Saturday
TBD | Bay Arena in Leverkusen, Germany | View Tickets |
| Bayer 04 Leverkusen vs. RB Leipzig | 5-2-2026
Saturday
TBD | Bay Arena in Leverkusen, Germany | View Tickets |
| VfB Stuttgart vs. Bayer 04 Leverkusen | 5-9-2026
Saturday
TBD | MHPArena in Stuttgart, Germany | View Tickets |
| Bayer 04 Leverkusen vs. Hamburger SV | 5-16-2026
Saturday
TBD | Bay Arena in Leverkusen, Germany | View Tickets |
